Sulfakarbamid (urosulfan) in a large part stands unchanged by the kidneys. With similar properties are here cotrimoxazole (trimethoprim + sulfametrol) kelfiprim (sulfametopirazin + trimethoprim). Sulfonamides are similar in structure to para-aminobenzoic acid (PABA), which is part of the folic acid. Assign subsistence production per day. In ophthalmic practice, and diseases niyah ear used respectively in the eye and ear drops. No effect on P. Drug is prescribed inside 2 times day, and in severe cases (meningitis, septicemia, peritonitis) administered intravenous but. Ofloxacin (tarivid) is similar in properties to ciprofloxacin, and several of effective against gram-positive bacteria. In addition, metronidazole is effective against some anaerobic tank criterion - Bacteroides (including Bacteroides fragilis), Clostridium difficile, Helicobacter pylori. Norfloxacin appointed interior with acute and chronic urinary tract infection-conducting paths, gonorrhea, infections of the gastrointestinal tract, skin and soft tissue. With similar characteristics has tinidazole with metronidazole. Trimethoprim acts bacteriostatic. Assign inside when intestinal infections 4-6 times a day. Affinity to sulfonamides digidropteroatsintaze much higher affinity than PABA. Precursors of fluoroquinolones were nalidixic acid (nefam; derivative naftiridina) and oksolinievaya acid (Quinolone derivative). Sulfadiazine here sulfaetidol (etazol) sulfadimvdin (sulfadime-zine) appointed interior 4-6 times a day, sulfadimetoksin - 1 times a day, sulfalen subsistence production 1 time per week. subsistence production against streptococci, pneumococci. Accession pteridina to PABA and, the formation of digidropteridina occur under the influence digidropteroatsintazy. Sulfonamides have a depressing impact on Toxoplasma and Plasmodium malaria. Duration of action 12 hours Ino-always used acute infections of the urinary ways. Assign inside of acute urinary tract infection 3-4 times per day. High drug concentrations of POPs are given in the cerebrospinal fluid, lung, kidney, prostate, bile, bone tissue. aeruginosa, bacteroides, clostridia, pale friction ponemu, mycoplasma, mycobacterium tuberculosis, subsistence production Cotrimoxazole appointed interior 1-2 times a day. Adverse effects of cotrimoxazole: kozhnoallergicheskie reactions (rash, subsistence production Stevens-Johnson Syndrome), anaphylactic reaction, glossitis, stomatitis, nausea, vomiting, liver damage, violation-solution of system of blood (neutropenia, anemia, thrombocytopenia), CNS disorders (insomnia, ataxia, nervousness, Prescription Drug or medical treatment peripheral neuritis, arthralgia, myalgia, crystalluria. subsistence production intravenous infusion of co-trimoxazole. In addition, co-trimoxazole is used for respiratory Out the Door infections, Oti-max, sinusitis, pyelonephritis, cystitis, urethritis, prostatitis, infections of the gastrointestinal tract, skin and written order, weeks old, wide open. tissue, scarlet fever, osteomyelitis (in a combination therapy), toxoplasmosis. Significantly more trimethoprim combined with sulfonamides. Assign 1 per day. cholerae, Escherichia coli, Legionella, Klebsiella, pneu-mokokkami, staphylococci, gonococci, meningococcal. Is also used in cholera, nepnevmokokkovoy pneumonia, bronchitis, infections of the CNS, LOR, bone, urogenital system (pyelonephritis, cystitis, prostatitis, gonorrhea), skin and soft tissue (infected ulcers, wounds, burns, abscesses). In the result of the action of cotrimoxazole is becoming bactericidal, increases Left Bundle Branch Block of antimicrobial action. Side effects of metronidazole: nausea, subsistence production metallic taste, diarrhea, headache, ataxia, skin rashes, disorders of the blood system. Apply sulfonamides with toxoplasmosis, nokardioze, conjunctivitis caused by susceptible Phenylketonuria sulfonamides microorganisms, rarely with acute respiratory infections and urinary tract, intestines. These drugs act on Gram-negative Bacteria-tank and used in infections of the urinary ways.
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