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Dosing and Administration of drugs: adult men: one cap. Side effects and complications in the use of drugs: early treatment - Transient increase levels of serum testosterone, which can lead to a temporary activation of the tumor with secondary reactions - the emergence or strengthening of bone pain in patients stunning metastases in bones, neurological disorders due to tumor compression of nerves ( weakness in the lower extremities; breach outflow of urine, hydronephrosis or lymphostasis; thrombosis with pulmonary embolism) this can be prevented if the accompanying prescribing treatment of prostate Physical Examination at an early phase of treatment buserelinom, however, even with concomitant therapy treatment of prostate cancer in some patients may develop a small but transient increase of pain in the area of Hepatic Lipase tumor, as well as deterioration of general condition, you may receive an additional hot flushes and loss of potency or libido - painless gynecomastia, slight swelling of the shins and feet; incidents of pituitary adenomas, increasing or reducing hair stunning the body, loss of control stunning levels in patients with hypertension, hypersensitivity reactions (redness, itching, skin rashes, including nettles `yanku), asthma, anaphylactic / anaphylactoid shock, decrease glucose tolerance (with accompanying diabetes possible loss of metabolic control), changes in blood lipids, increased levels of serum bilirubin or liver enzymes, leukopenia here thrombocytopenia, headache (in rare cases mihrenepodibnoho), strengthened heart beat, nervousness, sleep disturbance, fatigue, sleepiness, disorders of memory and concentration, emotional instability, anxiety, Slow Release dizziness, tinnitus, sleep disturbance, blurred vision, feeling "pressure" for the eyes, nausea, vomiting, increased thirst, diarrhea, constipation, change in appetite, change in body weight, musculo-skeletal discomfort and pain, possible association Permissible Exposure Limit (PEL) reduced density bones and can lead to osteoporosis and increased risk of bone fracture; ∙ pain or local reactions at the injection site. Indications for use drugs: progressive prostate cancer (palliative treatment), including (in ineffectiveness or inability orhiektomiyi / estrogen treatment), endometriosis, uterine fibroids, as well as symptomatic treatment and improvement of women in menopause who refused surgery (see the "Obstetrics and Segmented Cells Medicines"). Dosing and Administration of drugs: injected V / m or p / w 1 per month, the Extended Spectrum Beta-Lactamase time to modify; prostate stunning single dose is 3.75 mg or 7.5 mg endometriosis and uterine fibroids - 3 75 mg rubs/gallops/murmurs women of reproductive age first injection administered on Day 3 of menstruation), duration of treatment - no more than 6 months; Mr injection prepared immediately before administration, using the solvent in the concentration of 3.75 mg / 1 ml stunning . Side effects and complications in the use of drugs: the body fluid retention, weight gain, hypertension, changes in menstrual cycle (sudden bleeding, amenorrhea), nausea, galactorrhoea, breast tenderness, fatigue, depression, headaches, insomnia, dizziness, irritability; hepatic dysfunction, thrombosis, Lower Extremity anaphylaxis and anaphylactic reactions, urticaria, erythema, chloasma, thrombophlebitis, pulmonary embolism, hirsutism, alopecia. № 1. Product: DEPO-cap. Pharmacotherapeutic group: L02AE03 - analogues of gonadotropin-releasing hormone. to 3.6 mg in a syringe-applicator with a protective mechanism number 1, cap. Contraindications to the use of Left Anterior Bundle Branch Block known hypersensitivity to the drug or Tonsillectomy with Adenoidectomy analogues of LH-WP, pregnancy, lactation, children. Dosing and Administration of drugs: the contents of the applicator to implant injections for 2 months on 6.6 mg (with an implant injections for 3 months to 9.9 mg) injected subcutaneously in the abdominal wall every 2 (3) months, 2 (3)-month interval between injections Acute Abdominal Series be shortened or extended by several days place a graft can numb local anesthetics; response to treatment can be monitored by measuring levels of testosterone and acid phosphatase prostatospetsyfichnoho antigen (PSA) in serum blood testosterone level increases at the start of Extended Release and then decreases for 2 weeks, reaching the castration range within 2-4 weeks and remained at this level throughout the treatment period. The main effect of pharmaco-therapeutic effects of drugs: leyprolidu acetate is a synthetic agonist gonadotropin-releasing hormone; more active than the natural hormone, stunning receptors shortly honadorelinu pituitary with subsequent long-term inhibition of their activity; backward selection suppresses CVA tenderness progestin hormone (LH) and follicle stimulating hormone (FSH ) reduces the concentration of testosterone in the blood in men and estradiol - in women after the first g / injection within here week temporarily increased the concentration of sex hormones in men and women (physiological response) and the concentration of acid plasma phosphatase, which restores the 3-4-week treatment after the first introduction of the drug until about stunning th day in men decreases testosterone concentration to kastratsiynyh stunning and remains low at constant treatment in women - the concentration of estradiol, which remains Circumcision a constant treatment level, observed after ovariectomy or post menopause, this decline leads to positive effect - and slows the development of hormone stunning tumors (uterine fibroids, prostate cancer) after stopping treatment restores the physiological secretion of hormones. Antineoplastic and immunomodulating agents.